I have been using the calibre editor a lot and, for some reason, the Windows 10 "Open with" does not always show the calibre editor even if I have used it before with "Open with > Choose another app". So now I'm using "Edit with Calibre" on the context menu with the help of a simple Registry text file.
Copy and paste the 3 lines below into a Notepad text file with the extension .reg (for example: editcalibre.reg) and save it. Double click on the file and it will prompt you to update your Registry. Then you will be able to right-click on an epub book and select "Edit with Calibre".
[HKEY_CLASSES_ROOT\*\shell\Edit with Calibre]
[HKEY_CLASSES_ROOT\*\shell\Edit with Calibre\command]
@="C:\\Program Files\\Calibre2\\ebook-edit.exe \"%1\""
Copy and paste the 3 lines below into a Notepad text file with the extension .reg (for example: editcalibre.reg) and save it. Double click on the file and it will prompt you to update your Registry. Then you will be able to right-click on an epub book and select "Edit with Calibre".
[HKEY_CLASSES_ROOT\*\shell\Edit with Calibre]
[HKEY_CLASSES_ROOT\*\shell\Edit with Calibre\command]
@="C:\\Program Files\\Calibre2\\ebook-edit.exe \"%1\""